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首页 > 灵芝学者 > 台北医学大学 苏庆华教授

台北医学大学 苏庆华教授

2016-11-16 16:01:24    来源:台北医学大学    浏览:815次
  苏庆华,生于1947年,师承王西华教授,现任台北医学大学微生物免疫学科名誉教授,牙医学系教授,医学科学研究所教授,生医材料暨组织工程研究所讲座教授。

  1970年毕业于台湾大学园艺学系,1973年获得台湾大学园艺研究所硕士学位,1985年通过研究发现名为植生虫草(Phytocordyceps)的真菌属并将它的性别遗传模式及子实体形成的机制区分获得台湾大学农业化学研究所博士学位。在北医任教的第一年通过培养灵芝多糖供应灵芝整合性计划研究组织进行功能性研究开始了灵芝研究生涯。尔后相继研究了三萜类指纹图谱以作为灵芝种类分类依据、灵芝子实体废渣的再利用等相关领域。

  主要研究方向:微生物学、真菌学、灵芝三萜类分析及鉴定、生物医学材料、樟芝栽培及成分鉴定、冬虫夏草属、皮肤组织再生、白色念珠菌之性别遗传。



主要发表论文、著作:


1. 2014 Chang FM,Ou TY,Cheng WN,Chou ML,Lee KC,Lee KC. Short-Term Exposure to Fluconazole Induces Chromosome Loss in Candida albicans: An Approach to Produce Haploid Cells . Fungal Genetics and Biology .2014 ;(70):68-76

2. 2012 Chen LY,Sheu MT,Liao CK,Tsai FC,Kao wy,Kao wy. Taiwanofungus camphorauts (syn. Antrodia camphorata) extract and amphotericin B exert adjuvant effect via mitochondrial apoptotic pathway . Integrative Cancer Therapies .2012 ;(x):x-x

3. 2011 Yu SW,Kuo ST,Tuan WH,Tsai YY,Su CH. Ion release from three lead-free piezoelectric ceramics and their physical andcytotoxicity characteristics . Materials Letters .2011 ;(65):3522-3524

4. 2011 Chen LI,Sheu MT,Liu DZ,Liao CK,Ho HO,Ho HO. Pretreatment with an Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Enhances the Cytotoxic Effects of Amphotericin B . Journal of Agricultural and Food Chemistry .2011 ;(59):11255-11263

5. 2011 Liu HY,Wu AT,Tsai CY,Chou KR,Zeng R,Zeng R. The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis. . Biomaterials .2011 ;(32):6773-6778

6. 2011 Wei HJ,Wu AT,Hsu CH,Cheng WF,Su CH,Su CH. The Development of a Novel Cancer Immunotherapeutic Platform Using Tumor-targeting Mesenchymal Stem Cells and a Protein Vaccine . Molecular Therapy .2011 ;(19):2249-2257

7. 2010 Burnouf PA,Juan PK,Su CY,Kuo YP,Chou ML,Chou ML. A novel virally inactivated human platelet lysate preparation rich in TGF-β, EGF and IGF, and depleted of PDGF and VEGF . Biotechnol. Appl. Biochem. (2010) 56, 151–160 .2010 ;(56):151-160

8. 2009 Kuo YP,Lee YL,Tseng HT,Su CH,Burnouf T,Burnouf T. Influence of ethanol on the release of growth factors in human blood-derived platelet gels. . Biologicals .2009 ;(2009):1-8

9. 2009 Su CY,Kuo YP,Tseng YH,Su CH,Burnouf T. In vitro release of growth factors from platelet-rich fibrin (PRF): A proposal to optimized the clinical applications of PRF. . Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology .2009 ;(108):56-61

10. 2009 Liu KJ,Leu SJ,,Su CH,Chiang BL,Chen YL,Chen YL. Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma (accepted). . Immunolog .2009

11. 2008 Hsu SC,Ou CC,Li JW,Chuang TC,Kuo HP,Kuo HP. Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G(2)/M cell cycle arrest. . Journal of Ethnopharmacol .2008

12. 2008 Peng SC,Cheng CY,Sheu F,Su CH. The antimicrobial activity of heyneanol A extracted from the root of taiwanese wild grape . Journal of Applied Microbiology .2008 ;(105):485-479

13. 2008 Wang CC,Su CH,Chen CC. Water absorbing and antibacterial properties of N-isopropyl acrylamide grafted and collagen/chitosan immobilized polypropylene nonwoven fabric and its application on wound healing enhancement . J. Biomedical Materials Research Part A .2008 ;(84(A)):1006-1017

14. 2007 Chen KC,Peng CC,Peng RY,Su CH,Chiang HS,Chiang HS. Unique Formosan Mushroom Antrodia camphorata Differentially Inhibits Androgen-Responsive LNCaP and -Independent PC-3Prostate Cancer Cells . Nutrition and Cancer .2007 ;(57):111-121

15. 2007 Liu DZ,Liang YC,Lin SY,Lin SY,Wu WC,Wu WC. Antihypertensive activities of a solid-state culture of Taiwanofungus camphoratus (Chang-chih) in spontaneously hypertensive rats . Bioscience, Biotechnology & Biochemistry .2007 ;(71):23-30

16. 2007 Liu DZ,Liang HJ,Chen CH,Su CH,Lee TH,Lee TH. Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action . J. of Ethnopharmacology .2007 ;(109):93-103

17. 2006 Peng CC,Chen KC,Peng RY,Su CH,Hsieh-Li HM. Antrodia camphorata Extract Induces Replilcative Senescence in Superficial TCC, and Inhibits the Absolute Migration Capability in Invasive Bladder Carcinoma Cells . Journal of Ethnopharmacology .2006 ;(109):93-103

18. 2006 Chen. WH,Lo. WC,Lee. JJ,Su CH,Lin CT,Lin CT. Tissue-Engineered Intervertebral Disc and Chondogenesis Using Human Nuleeus Polposus Regulated through TGF-beta1 in Platelet-Rich Plasma . Journal of Cellular Physiology .2006 ;(209):744-754

19. 2006 Peng. CC,Chen. KC,Peng. RY,Su. CH,Hsieh-Li HM. Human Urinary Bladder Cancer T24 Cells are Susceptible to the Antrodia camphorata extracts . Cancer Letters .2006 ;(243):109--119

20. 2005 Su CH,Liu SH,Yu SY,Hsieh YL,Ho SO,Ho SO. Development of fungal mycelia as a skin substitute:Characterization of keratinocyte proliferation and matrix metalloproteinase expression during improvement in the wound-healing process . Journal of Biomedical Materials Research Part A .2005 ;(72A):220-227

21. 2004 Wu SH,Yu ZH,Dai YC,Chen CT,Su CH,Su CH. Taiwannofungus, a polypore new genus . Fungal Science .2004 ;(19):109-116

22. 2004 Chao SC,Hsieh IL,Lee LW,Cheng KD,Su CH. Culture of Cordyceps myrmecophila Cesati . Fungal Science .2004 ;(19):49-55

23. 2004 Yang L,Yeh SD,Xie S,Altuwaijri S,Ni J,Ni J. Androgen suppresses PML protein expression in prostate cancer CWR22R Cells . Biochem. Biophys. Res. Commun. .2004 ;(314):69-75

24. 2004 Hung WS,Lai WF,Leu B,Su CH,Fang CL,Fang CL. Effect of SACCHACHITIN on keratinocyte proliferation and the expressions of type I collagen and tissue-transglutaminase during skin wound healing . Journal Biomedical Material Research Part B: Applied Biomaterials .2004 ;(70B):122-129

25. 2003 Su CH, Chao SC, Lee LW, IL Hsieh, Cheng KT. Phylogenetic relationships of Cordyceps species revealed by ITS sequences of ribosoomal DNA . J. Genetic and Molecular Biology .2003 ;(14):30-40

26. 2003 Hsiao G, Shen MY, Lin KH, Lan MH, Wu LY, Chou DS, Lin CH, Su CH, Sheu JR. Antioxidative and hepatoprotective effects of Antrodia camphorata extract . Journal of Agricultural and Food Chemistry .2003 ;(51):3302-3308

27. 2001 Su CH,Yang YZ , Ho HO,Hu CH and Sheu MT. High-performance liquid chromatographic analysis for characterization of triterpenoids from Ganoderma . J. Chromatography Research .2001 ;(39):93-100

28. 2001 Huang WS, Fang CL, Su CH , Lai WF , Chang WC, and Tsai YW. Cytotoxicity and immunogenecity of SACCHACHITIN and its mechanism of action on skin wound healing . J. Biomedical Research .2001 ;(56):93-100

29. 2001 Yang YZ, Sun CS Juan SW, Chen PH, Chan MH, Lee LW and Su CH. Utilization of fruiting bodies from genus Ganoderma . Fungal Science .2001 ;(16):23-32

30. 2001 Chen CJ, Su CH and Lan MH. Study on solid cultivation and bioactivity of Antrodia camphorata . Fungal Science .2001 ;(16):65-72

31. 2001 Wang JC, Hu SH, Su CH and Lee TM. Antitumor and immunoenhancing activities of polysaccharide from culture broth of Hericium spp. . Kaohsiung Journal of Medical Sciences .2001 ;(17):461-467

32. 1999 Lee LW, Peng HC, Ko WC, Hung WC, Su CH, Lin CH, Huang TF, Yen MH and Sheu JR. Triflavin potentiates the antiplatelet activity of platelet activating factor receptor antagonist on activated neutrophil-induced platelet aggregation. . Eur. J. Pharmacol. .1999 ;(364):239-264

33. 1999 Su CH, Sun CS, Juan SW, Ho HO, Hu CH and Sheu MT. Development of fungal mycelia as skin substitutes: Effects on the wound healing process. . NTJM .1999 ;(1):31-39

34. 1999 Sheu JR, Hung WC, Su CH, Lin CH, Lee LW, Lee YM and Yen MH. The antiplatelet activity of escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway. . Eur J Haematol .1999 ;(62):317-326

35. 1999 Su CH, Sun CS, Juan SW, Ho HO, Hu CH and Sheu MT. Development of fungal mycelia as skin substitutes: Effects on wound healing and fibroblast. . Biomaterials .1999 ;(20):61-68

36. 1998 Sheu JR, Kan YC, Hung WC, Su CH, Lin CH, Lee YM and Yen MH. The antiplatelet activity of rutaecarpine, an alkaloid isolated from evodia rutaecarpa, is mediated through inhibition of phospholipase C. . Throm. Res. .1998 ;(92):53-64

37. 1998 Cheng KT, Su CH, Chang HC and Huang JY. Differentiation of genuines and counterfeits of cordyceps species using random amplified polymorphic DNA. . Planta Medica .1998 ;(64):451-453

38. 1997 Cheng KT, Chang HC, Su CH and Hsu FL. Identification of dried rhizomes of Coptis species using random amplified polymorphic DNA. . Bot. Bull. Acad. Sin. .1997 ;(38):241-244

39. 1997 Sheu JR, Yen MH, Hung WC, Lee YM, Su CH and Huang TF. Triflavin inhibits platelet-induced vasocontraction in deendothelialized aorta. Arterioscl. . Thromb. Vas. Biol. .1997 ;(17):3461-3468

40. 1997 Su CH, Sun CS, Juan SW, Hu CH, Ke WT and Sheu MT. Fungal mycelia as the source of chitin and polysaccharides and their application as skin substitutes. . Biomaterials .1997 ;(18):1169-1174

41. 1996 Su CH, Juan SW, Sun CS and Tung IC. Application of extracted waste from basidiomes of Ganoderma for Healing enhancement of skin wounds. . Mushroom Biology and Mushroom Products .1996

42. 2004 Su CH,Lin BW,Yu SY,Liu SW. Use of Ganoderma tsugae for the treatment of Human Chronic Skin Ulcers . Mushroom Science .2004 ;(XVI):659-662

43. 2003 Lan CM, Deng WP, Lin CH, Tai YH, Hsieh YL, Su CH. Physiological Activities of Antrodia camphorata, a unique fungal species in Taiwan . Proceedings, The 2nd International Conference on Medical Mushroom (InCoMM) 2003 .2003

44. 2003 Su CH, Hseu MC, Tai YW, Yu SY, Liu SW, Hsieh YL, Hu CH. Sacchachitin, a skin wound dressing material from Ganoderma tsugae . Proceedings, The 2nd International Conference on Medicinal Mushroom (InCoMM) 2003 .2003

45. 2002 Su CH. The utilization of waste from fruiting body of Ganoderma for healing enhancement on human chronic skin ulcer . Proceedings, The 8th International Symposium of Mycological Society of Japan (Part II)- New frontier in health science associated with the fungi .2002